The official site of
The Mahal Laboratory
Developing and utilizing cutting edge chemical and systems biology tools to understand glycosylation in human health and disease.
Located in the Department of Chemistry at the University of Alberta the Mahal Laboratory specializes in developing and utilizing cutting edge chemical and systems biology tools to understand glycosylation in human health and disease.
PROF. MAHAL is the CANADA EXCELLENCE RESEARCH CHAIR IN GLYCOMICS
For the past 17 years the Mahal Laboratory has been at the forefront of creating and utilizing systems-based approaches to decode the glycome. In 2005, we created lectin microarray technology, a simple, yet powerful tool to profile the glycosylation of complex samples.
We are pioneers in the area of systems glycobiology, using our unique dual-color lectin microarray approach. This modification, enables semi-quantitative glycan analysis, allowing us to easily combine our data with other datasets (e.g. transcriptome, miRNA). Our integration of the glycome with other data has led to insights in melanoma metastasis, a new understanding of glycan regulation via miRNA and a new hypothesis on the role of miRNA in identifying functionally relevant genes (miRNA proxy approach).